New CCI Uppercut .22LR Self-Defense Ammunition

Hrachya H
by Hrachya H
CCI Uppercut (1)

Although the .22 Long Rifle is not generally considered a good defensive round, there are still people who use firearms chambered in .22LR for self-defense purposes. There can be many reasons for opting for a .22LR gun such as weak grip strength, recoil sensitivity, price, etc. Well, for those who chose the .22LR for defensive use, CCI Ammunition has a new product – the CCI Uppercut, a self-defense .22LR ammunition optimized for semi-auto pistols with 2.5″ to 4″ barrels. Let’s take a look.


Protection should always be personal. Built for how you carry. Crafted for how you defend. Sized to match any shooter. CCI Uppercut answers that call, with power and performance traditional 22 LR ammunition has never been able to deliver.

CCI Uppercut (5)

CCI Uppercut cartridges are loaded with 32-grain jacketed hollow point bullets that are launched at a muzzle velocity of 950 feet per second (out of a typical short-barreled handgun) which will result in a muzzle energy of 64 foot pounds. The jacketed bullets are used to decrease barrel fouling and allow for uniform, consistent and reliable expansion. The advertised penetration depth in ballistic gelatin is 8 to 10 inches. CCI notes that the Uppercut ammo is not designed to provide deep penetration, the priority here is expansion and weight retention.

CCI Uppercut (7)

Check Prices on CCI Uppercut Ammunition

The MSRP of CCI Uppercut ammunition is $12.99 for a box of 50 cartridges. To learn more about the design of CCI Uppercut rounds and the concept of defensive .22LR in general, read the CCI article here.

For those of you who use .22LR for self-defense, let us know in the comments section what you think about this new offering from CCI.

Pictures by CCI Ammunition,

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Hrachya H
Hrachya H

Managing Editor Being a lifelong firearms enthusiast, Hrachya always enjoys studying the history and design of guns and ammunition. Should you need to contact him, feel free to shoot him a message at

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2 of 27 comments
  • KsKLR KsKLR on Feb 13, 2024

    I wouldn’t recommend a 22 pistol for self defense, but where applicable a compact 22 rifle with a good light and a rds could put 10 rounds in the head with little effort. I’ve always said, if I could only have one firearm, it would be a good 22 rifle.

  • Bcmarshall3285 Bcmarshall3285 on Feb 13, 2024

    March 30, 1981. 4x "one shot stops" from a junker RG .22 almost changed the course of history in the US. Don't overthink "stopping power" or think lethality is the only gauge of ammunition capability.